Epidemiology Research - Twin Studies, Statistics, Environmental and Genetic Factors

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Renal colic in Pisa emergency department: epidemiology, diagnostics and treatment patterns.

Cupisti A, Pasquali E, Lusso S, Carlino F, Orsitto E, Melandri R

U.O. Nefrologia e Dialisi, Azienda Ospedaliero-Universitaria Pisana, Via Roma 67, 56100, Pisa, Italy.

The present investigation aimed to point out some epidemiological and clinical features of renal colic in our region. All emergency department (ED) visits performed from 1 January to 31 December 2005 were reviewed to select those with diagnosis of renal colic or kidney stones. There were 70,621 visits to the University of Pisa ED. Renal colic or stone were diagnosed in 696 cases (1%); 21.6% of them were recurrent stone formers; the males to female ratio was 1.4-1. The age distribution showed a higher rate from 25 to 44 years of age, whereas seasonal distribution showed a higher risk during summer months, particularly in July. Ultrasonography (US) was the only examination in 70.2% cases, it was coupled with plain abdomen X-ray (KUB) in 10% of the cases. NSAIDs were always used (100%), sometimes in association with opiate (15.8%) or with anti-cholinergic (26.5%) medications. The data of our investigation are in a substantial agreement with the reported literature as far as concerns the main epidemiological features of renal colic and its treatment. On the contrary, the diagnostic approach is mainly based on US whereas KUB is rarely performed. Until the 31st of December 2005, CT-scan was not used as the first and only imaging study in cases of renal colic. This different diagnostic approach may be linked to financial and cultural reasons, and structural and functional organization of the National Health Service facilities.

Published 25 April 2008 in Intern Emerg Med.
Full-text of this article is available online (may require subscription).


Articles on Epidemiology published 25 April 2008:

Epidemiology of hepatitis C virus infection in HIV-infected individuals.   J Viral Hepat.

Many individuals are infected with both HIV and hepatitis C virus (HCV) infection. More rapid progression of liver disease is seen, higher levels of HCV RNA encourage transmission and sustained virological responses are lower in coinfected patients. The management of these patients is further complicated by potential interactions between antiretroviral therapy and peginterferon and ribavirin. [Abstract] [Full-text]


Articles on Epidemiology published 24 April 2008:

Epidemiology and Outcome of Tachyarrhythmias in Tertiary Pediatric Cardiac Centers.   Cardiology, 111(3): 191-196.

Introduction: Little is known about the real importance of pediatric arrhythmias. Methods: We analyzed the epidemiology, presentation and outcome of all clinically relevant tachyarrhythmias followed up in our pediatric institutions from 1995 to 2006. Results: A total of 250 cases were identified. The mean age +/- SD at diagnosis was 4.7 +/- 5.3 years, 45 cases were neonatal (18%). Supraventricular arrhythmias were noted in 210 children (84%), ventricular arrhythmias in 40 (16%). The most ... [Abstract] [Full-text]

A Population-Based Study of the Incidence and Molecular Epidemiology of Methicillin-Resistant Staphylococcus aureus Disease in San Francisco, 2004-2005.   Clin Infect Dis.

Background. @nbsp; Methicillin-resistant Staphylococcus aureus (MRSA) infections have become a major public health problem in both the community and hospitals. Few studies have characterized the incidence and clonal composition of disease-causing strains in an entire population. Our objective was to perform a population-based survey of the clinical and molecular epidemiology of MRSA disease in San Francisco, California. Methods. @nbsp; We prospectively collected 3985 MRSA isolates and ... [Abstract] [Full-text]

Changing Epidemiology of Pneumococcal Meningitis after the Introduction of Pneumococcal Conjugate Vaccine in the United States.   Clin Infect Dis.

Background. @nbsp; Although hospitalizations due to invasive pneumococcal disease decreased after routine vaccination of young children with a 7-valent pneumococcal conjugate vaccine (PCV7) began in 2000, information on the trends in pneumococcal meningitis is limited. Methods. @nbsp; We estimated national trends in rates of hospitalization for pneumococcal meningitis, using data from the Nationwide Inpatient Sample, 1994-2004. Pneumococcal meningitis cases and deaths were identified on the ... [Abstract] [Full-text]


Articles on Epidemiology published 23 April 2008:

Anemia in chronic obstructive pulmonary disease: epidemiology and economic implications.   Curr Med Res Opin, 24(4): 1123-30.

BACKGROUND: Anemia in chronic illness is associated with increased healthcare resource utilization (HRU) and costs. In COPD, it occurs frequently and influences both clinical and economic outcomes. Because no data studies have been performed either in a single center or a subpopulation of COPD patients, anemia's influence on the outcomes is not fully understood. RESEARCH DESIGN AND METHODS: We conducted a retrospective cohort study in a large healthcare database to quantify prevalence, HRU and ... [Abstract] [Full-text]


Articles on Epidemiology published 22 April 2008:

The molecular epidemiology of HIV-1 envelope diversity during HIV-1 subtype C vertical transmission in Malawian mother-infant pairs.   AIDS, 22(7): 863-71.

OBJECTIVES: To study the relationship between HIV-1 subtype C genetic diversity and mother-to-child transmission and to determine if transmission of HIV-1 V1/V2 env variants occurs stochastically. DESIGN: Case-case-control study of Malawian mother-infant pairs consisting of 32 nontransmitting women, 25 intrauterine transmitters, and 23 intrapartum transmitters in Blantyre, Malawi. METHODS: A heteroduplex tracking assay against the highly variable HIV-1 env V1/V2 region was used to characterize ... [Abstract] [Full-text]

Survival differences between patients with scalp or neck melanoma and those with melanoma of other sites in the Surveillance, Epidemiology, and End Results (SEER) program.   Arch Dermatol, 144(4): 515-21.

OBJECTIVE: To compare the prognosis of patients with scalp or neck (scalp/neck) melanomas with that of patients with melanomas at other sites in a large, population-based national data set controlling for known prognostic factors. DESIGN: Retrospective cohort study using US cancer registries that constitute the Surveillance, Epidemiology, and End Results 13 Registries (SEER-13) database. PATIENTS: A total of 51 704 non-Hispanic white adults in the United States with a first invasive cutaneous ... [Abstract] [Full-text]

Epidemiology, clinical and economic outcomes of admission hyponatremia among hospitalized patients.   Curr Med Res Opin.

BACKGROUND: Hyponatremia, the most frequent electrolyte derangement identified among hospitalized patients, is associated with worsened outcomes in patients with pneumonia, heart failure and other disorders. RESEARCH DESIGN AND METHODS: We performed a retrospective cohort study of hospitalized patients to quantify the attributable influence of admission hyponatremia on hospital costs and outcomes. Data were derived from a large administrative database with laboratory components, representing ... [Abstract] [Full-text]


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Epidemiology Research Today Archive:

Volume 1 (2005)
  Issue 1 (September)
  Issue 2 (October)
  Issue 3 (November)
  Issue 4 (December)

Volume 2 (2006)
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  Issue 2 (February)
  Issue 3 (March)
  Issue 4 (April)
  Issue 5 (May)
  Issue 6 (June)
  Issue 7 (July)
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  Issue 11 (November)
  Issue 12 (December)

Volume 3 (2007)
  Issue 1 (January)
  Issue 2 (February)
  Issue 3 (March)
  Issue 4 (April)
  Issue 5 (May)
  Issue 6 (June)
  Issue 7 (July)
  Issue 8 (August)
  Issue 9 (September)
  Issue 10 (October)
  Issue 11 (November)
  Issue 12 (December)

Volume 4 (2008)
  Issue 1 (January)
  Issue 2 (February)
  Issue 3 (March)
  Issue 4 (April)



Epidemiology Books

Survival Analysis: A Self-Learning Text (Statistics for Biology and Health)

Survival Analysis: A Self-Learning Text (Statistics for Biology and Health)