Epidemiology Research - Twin Studies, Statistics, Environmental and Genetic Factors

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Differences in epidemiology of MDS between Western and Eastern countries: Ethnic differences or environmental influence?

Kuendgen A, Matsuda A, Germing U

Department of Hematology, Oncology and Clinical Immunology, Heinrich-Heine-University, Moorenstr. 5, 40225 Düsseldorf, Germany. Kuendgen@med.uni-duesseldorf.de

Myelodysplastic syndromes show ethnic differences. Several investigators have reported a striking difference in age at diagnosis between Eastern and Western MDS patients. Referring to a letter bei Paydas speculating about toxic environmental influences as a possible cause for younger age in Asian MDS patients, we discuss our experience from a direct comparison of Japanese and German MDS, in particular refractory anemia patients.

Published 19 November 2006 in Leuk Res, 31(1): 103-4.
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