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Molecular epidemiology of the sil streptococcal invasive locus in group A streptococci causing invasive infections in French children.

Bidet P, Courroux C, Salgueiro C, Carol A, Mariani-Kurkdjian P, Bonacorsi S, Bingen E

Université Paris VII, UFR Médicale; EA 3105, Laboratoire d'Etudes de Génétique Bactérienne dans les Infections de l'Enfant; Assistance Publique-Hôpitaux de Paris (AP-HP), Service de Microbiologie, Hôpital Robert Debré, Paris, France.

We found 31 different emm-toxin genotypes among 74 group A streptococcal isolates causing invasive infections in French children. The predominant emm types were emm1 (25%), emm3 (8%), emm4 (8%), emm6 (7%), and emm89 (9%). Sixteen percent of isolates harbored the streptococcal invasive locus, half of them belonging to emm4.

Published 5 June 2007 in J Clin Microbiol, 45(6): 2002-4.
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