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Molecular epidemiology and clinical manifestations of viral gastroenteritis in hospitalized pediatric patients in Northern Taiwan.

Chen SY, Chang YC, Lee YS, Chao HC, Tsao KC, Lin TY, Ko TY, Tsai CN, Chiu CH

Division of Pediatric Gastroenterology, Chang Gung University College of Medicine, Kweishan 333, Taoyuan, Taiwan.

By reverse transcription-PCR or PCR, among 257 children with nonbacterial acute gastroenteritis (AGE), rotavirus, norovirus, astrovirus, enteric adenovirus, and multiple viruses were identified in 78 (30.4%), 21 (8.2%), 7 (2.7%), 51 (19.8%), and 53 (20.6%) patients, respectively. Higher disease severity was found for AGE caused by multiple viruses and by rotavirus alone. The majority of rotaviruses isolated from 2004 to 2006 belonged to genotypes G1 (20.4%), G2 (16.5%), G3 (27.2%), and G9 (21.4%).

Published 5 June 2007 in J Clin Microbiol, 45(6): 2054-7.
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