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Sclerosing cholangitis epidemiology and etiology.

Lazaridis KN

Center for Basic Research in Digestive Diseases, Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA. lazaridis.konstantinos@mayo.edu

Sclerosing cholangitis represents a spectrum of chronic biliary diseases that either has an unknown etiology (i.e., primary) or is caused by identifiable insults to the biliary tree (i.e., secondary). To date, the epidemiology of primary sclerosing cholangitis has been appraised; however, its etiology continues to be unclear. In contrast, the etiology of secondary sclerosing cholangitis is always known, but the epidemiology of this clinical entity is difficult to study.

Published 6 February 2008 in J Gastrointest Surg, 12(3): 417-9.
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